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Naltrexone will help you avoid drugs and alcohol only as long as you are taking it. Its overall benefit has been described as "modest". The person takes the medication about an hour (and only then) before drinking to avoid side effects that arise from chronic use. During pregnancy, this medication should be used only when clearly needed. This medication must not be used in people currently taking opiates, including methadone. Doing so can cause sudden withdrawal symptoms. Talk to your doctor if you are using marijuana. Talk to your pharmacist for more details. With additional contingency management support, naltrexone may be effective in a broader population. It is unclear if use is safe during pregnancy. Use naltrexone regularly to get the most benefit. It is also marketed in combination with bupropion (bupropion/naltrexone) as Contrave and was marketed with morphine (morphine/naltrexone) as Embeda. Before using this medication, tell your doctor or pharmacist your medical history, especially of: current or recent use (in the last 7 to 14 days) of any type of opioid drug (such as morphine, methadone, buprenorphine), kidney disease, liver disease. Naltrexone was first made in 1965 and was approved for medical use in the United States in 1984.

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