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Talk to your doctor if you are using marijuana. After stopping naltrexone treatment, you may be more sensitive to lower doses of opioids, increasing your risk of possibly life-threatening side effects from the narcotic (e.g., decreased breathing, loss of consciousness). To help you remember, take it at the same time each day. Effects begin within 30 minutes. This may help you drink less or stop drinking completely. The challenge involves giving a test dose of naloxone and monitoring for opioid withdrawal. Naltrexone may be taken with food or antacids if stomach upset occurs. Your doctor may occasionally change your dose to make sure you get the best results. Naltrexone may cause liver damage when taken in large doses. Your doctor may give you another medication (naloxone challenge test) to check for opiate use. Use naltrexone regularly to get the most benefit. It is also marketed in combination with bupropion (bupropion/naltrexone) as Contrave and was marketed with morphine (morphine/naltrexone) as Embeda. Naltrexone is also used to treat alcoholism by reducing your urge to drink alcohol. Your doctor may occasionally change your dose to make sure you get the best results. Avoid alcoholic beverages. The challenge involves giving a test dose of naloxone and monitoring for opioid withdrawal.

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