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In those still on opioids, opioid withdrawal may occur. Your doctor may give you another medication (naloxone challenge test) to check for opiate use. It also decreases the desire to take opiates. Naltrexone is only helpful when it is used as part of an addiction treatment program. Consult your doctor before breast-feeding. It has benefits over methadone and buprenorphine in that it is not a restricted medication. Naltrexone is also used to treat alcoholism by reducing your urge to drink alcohol. The most common side effects reported with naltrexone are gastrointestinal complaints such as diarrhea and abdominal cramping. When naltrexone is taken at home, it is usually taken once a day with or without food. Naltrexone should not be started until several (typically 7-10) days of abstinence from opioids have been achieved. The Sinclair method is a method of using opiate antagonists such as naltrexone to treat alcoholism. Continue to take naltrexone even if you feel well. Naltrexone may cause liver damage when taken in large doses. It carries an FDA boxed warning for this rare side effect. Naltrexone is only helpful when it is used as part of an addiction treatment program.

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