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Effects begin within 30 minutes. Your doctor may occasionally change your dose to make sure you get the best results. This drug may make you dizzy. The challenge involves giving a test dose of naloxone and monitoring for opioid withdrawal. Talk to your pharmacist for more details. Naltrexone is only part of a complete treatment program that may also include additional forms of counseling and/or monitoring. When naltrexone is taken in a clinic or treatment center, it may be taken once a day, once every other day, once every third day, or once every day except Sunday. While some do well with this formulation, it must be taken daily, and a person whose cravings become overwhelming can obtain opioid intoxication simply by skipping a dose. The challenge involves giving a test dose of naloxone and monitoring for opioid withdrawal. This is due to the risk of acute opioid withdrawal if naltrexone is taken, as naltrexone will displace most opioids from their receptors. Naltrexone may be taken with food or antacids if stomach upset occurs. Use naltrexone regularly to get the most benefit. Your doctor may recommend that naltrexone be given to you by a family member or other caregiver.

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