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The most common side effects reported with naltrexone are gastrointestinal complaints such as diarrhea and abdominal cramping. Effects begin within 30 minutes. Naltrexone has been shown to decrease the amount and frequency of drinking. Naltrexone should not be started until several (typically 7-10) days of abstinence from opioids have been achieved. The opioid antagonist blocks the positive-reinforcement effects of alcohol and allows the person to stop or reduce drinking. Use is not recommended in people with liver failure. Subsequent studies have suggested limited toxicity in other patient populations. Naltrexone is not a cure for drug addiction or alcoholism. This drug may make you dizzy. Naltrexone is or has been marketed under a variety of brand names, including Adepend, Antaxone, Celupan, Depade, Nalorex, Narcoral, Nemexin, Revia/ReVia, Trexan, and Vivitrol. When naltrexone is taken in a clinic or treatment center, it may be taken once a day, once every other day, once every third day, or once every day except Sunday. This may help you drink less or stop drinking completely. This medication blocks the effects of opiate drugs (including heroin) and similar drugs (opioids). It is not likely that naltrexone will cause liver damage when taken in recommended doses. Make sure you completely understand and accept the risks and benefits of using this medication.

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