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Follow your doctor's instructions closely. With additional contingency management support, naltrexone may be effective in a broader population. An opioid is sometimes called a narcotic. A combination of naltrexone with buprenorphine (buprenorphine/naltrexone) has been developed, but has not been marketed. Naltrexone may cause liver damage when taken in large doses. Use naltrexone regularly to get the most benefit. It can help people drink less alcohol or stop drinking altogether. Use naltrexone regularly to get the most benefit. Naltrexone should not be started until several (typically 7-10) days of abstinence from opioids have been achieved. Discuss the risks and benefits with your doctor. This medication blocks the effects of opiate drugs (including heroin) and similar drugs (opioids). The opioid antagonist blocks the positive-reinforcement effects of alcohol and allows the person to stop or reduce drinking. Your doctor may give you another medication (naloxone challenge test) to check for opiate use. Naltrexone may be taken with food if it upsets your stomach. Naltrexone by mouth remains an ideal treatment for a small number of people with opioid use, usually those with a stable social situation and motivation. Naltrexone is used to prevent relapse in people who became dependent on opioid medicine and then stopped using it.

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