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Your doctor may give you another medication (naloxone challenge test) to check for opiate use. Use naltrexone regularly to get the most benefit. If withdrawal occurs, naltrexone should not be started. Naltrexone is used to prevent relapse in people who became dependent on opioid medicine and then stopped using it. Do not take more or less of it or take it more often than prescribed by your doctor. However, large doses of heroin or narcotics can overcome this block. Naltrexone may also be used for purposes not listed in this medication guide. A decreased desire for opioids, though, may take a few weeks. You may need to stop certain opiate drugs (such as methadone) 10 to 14 days before starting naltrexone. Talk to your pharmacist for more details. Dosage is based on your medical condition and response to treatment. Use naltrexone regularly to get the most benefit. While some do well with this formulation, it must be taken daily, and a person whose cravings become overwhelming can obtain opioid intoxication simply by skipping a dose. Naltrexone can help keep you from feeling a "need" to use the opioid. Avoid alcoholic beverages. Naltrexone may cause liver damage when taken in large doses. Keep the bottle tightly closed when not in use. Side effects may include trouble sleeping, anxiety, nausea, and headaches.

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