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Store at room temperature away from moisture and heat. After taking naltrexone, your body will be more sensitive to opioids. Follow all directions on your prescription label. This medication is also used to treat alcohol abuse. Do not take more or less of it or take it more often than prescribed by your doctor. It has benefits over methadone and buprenorphine in that it is not a restricted medication. Continue to take naltrexone even if you feel well. Naltrexone was first made in 1965 and was approved for medical use in the United States in 1984. You should not take naltrexone if you have recently stopped using opioid medications or opioid street drugs and are now experiencing withdrawal symptoms. Do not use this medicine in larger or smaller amounts or for longer than recommended. Before taking naltrexone, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. A combination of naltrexone with buprenorphine (buprenorphine/naltrexone) has been developed, but has not been marketed. It carries an FDA boxed warning for this rare side effect. Concerns for liver toxicity initially arose from a study of nonaddicted obese patients receiving 300 mg of naltrexone. Naltrexone comes as a tablet to take by mouth either at home or under supervision in a clinic or treatment center.

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